Principal Scientist H-1B Salary

291 certified H-1B filings list the job title Principal Scientist (FY2023–FY2026). The median offered base salary is $140,910; the middle half of filings fall between $115,595 and $161,000. The largest sponsor for this title is Regeneron Pharmaceuticals, Inc. (40 filings).

291
certified filings
$140,910
Median base salary
$115,595
25th pct
$161,000
75th pct
$176,000
90th pct
$99,900
10th pct
Estimates from public U.S. Department of Labor records — wages are employer-attested offered wages, not verified salaries paid; counts are filings, not people. Not legal, financial, or career advice. See our disclaimer & terms.
Data: DOL filings FY2023–FY2026 (through June 2026) · Page updated November 2026
$99,900$140,910 median$176,000

Salary by fiscal year

YearFilingsMedian
FY202688$153,735
FY202587$135,000
FY202453$140,000
FY202363$133,000

Top cities

CityFilingsMedian
Tarrytown, NY23$159,781
Cambridge, MA20$158,500
South San Francisco, CA12$164,646
Boston, MA8$127,500
Philadelphia, PA6$97,427
Collegeville, PA5$97,500
Seattle, WA5$159,650
Watertown, MA5$169,093
Andover, MA4$121,578
New Brunswick, NJ4$138,890
Pensacola, FL4$130,543
San Diego, CA4$117,072
Atlanta, GA3$127,338
Cranbury, NJ3$115,000
Denville, NJ3$108,800
Devens, MA3$138,020
Ewing, NJ3$115,000
Fairfield, NJ3$105,000
Framingham, MA3$136,552
New York, NY3$116,207

Principal Scientist salary by employer

Top 50 sponsors by number of filings. Click a column to sort.

EmployerFilingsMedian salary
Regeneron Pharmaceuticals, Inc.40$159,918
Bristol-Myers Squibb Company21$148,526
PFIZER INC.11$107,099
Amgen Inc.7$161,000
Eli Lilly and Company7$119,110
GlaxoSmithKline LLC7$97,500
AMERICAN CANCER SOCIETY, INC.6$110,510
Sanofi US Services Inc.6$136,406
Zoetis, Inc.6$124,692
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.5$155,000
Genentech, Inc.5$144,900
Novartis Institutes for BioMedical Research, Inc.5$116,355
TCG GreenChem, Inc5$115,000
Calder Biosciences Inc.4$134,000
Intellia Therapeutics4$160,875
Janssen Research & Development, LLC4$169,650
Roche Molecular Systems, Inc.4$114,400
Cytiva US LLC3$130,543
ELC Beauty LLC3$126,250
Intellia Therapeutics, Inc.3$172,100
Medtronic, Inc.3$127,358
RICONPHARMA, LLC3$108,800
STIRA PHARMACEUTICALS LLC3$105,000
The Children's Hospital of Philadelphia3$88,046
Tulex Pharmaceuticals Inc.3$115,000
Adare Pharmaceuticals Inc.2$119,000
Alamar Biosciences, Inc.2$215,930
Alnylam US, Inc.2$169,500
Arranta Bio MA LLC2$154,546
DeepNephro, Inc.2$110,000
ElectraTect, Inc.2$112,237
Epic Pharma LLC2$130,000
Eurofins Professional Scientific Services Mid-Atlantic, LLC.2$65,880
Hazen and Sawyer, D.P.C.2$112,902
Honda Research Institute USA, Inc.2$233,784
Ionis Pharmaceuticals, Inc.2$137,280
JangoBio LLC2$72,418
Nobell Foods, Inc.2$150,233
PHARMAVITE LLC2$124,500
PPD Development, L.P.2$103,555
Repertoire Immune Medicines, Inc.2$156,567
Unnatural Products Inc.2$172,500
Waters Technologies Corporation2$126,940
ABB Inc.1$101,700
Aclaris Therapeutics, Inc.1$89,378
Actavis Laboratories UT, Inc.1$127,385
Adobe Inc.1$215,000
Aizen Therapeutics, Inc.1$137,000
Akebia Therapeutics, Inc.1$185,166
Alcon Research, LLC1$94,182

Related job titles

Principal Data Scientist $175,000Principal Scientist I $114,004Principal Research Scientist $168,573Scientist $100,000Principal $245,000Data Scientist $119,000Research Scientist $150,000Principal Engineer $165,000Staff Scientist $76,491Senior Scientist $117,026

Estimates from public U.S. Department of Labor records — wages are employer-attested offered wages, not verified salaries paid. Not legal, financial, or career advice. Full disclaimer